The insulysin (insulin degrading enzyme) enigma

The insulysin (insulin degrading enzyme) enigma

There are many cellular locations proposed for insulysin, yet there is a lack of a definitive study that clearly establishes within which cellular compartment insulin and amyloid beta peptide hydrolysis occurs. The enigma of the insulin degrading enzyme is explored.

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Bibliographische Detailangaben
Veröffentlicht in:Cellular and molecular life sciences : CMLS 2006-11, Vol.63 (21), p.2432-2434
1. Verfasser: Hersh, L B
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cellular biology
Enzymes
Humans
Insulin
Insulin - metabolism
Insulysin - chemistry
Insulysin - genetics
Insulysin - metabolism
Mice
Molecular biology
Receptor, Insulin - metabolism
Visions & Reflections
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Beschreibung
Zusammenfassung:There are many cellular locations proposed for insulysin, yet there is a lack of a definitive study that clearly establishes within which cellular compartment insulin and amyloid beta peptide hydrolysis occurs. The enigma of the insulin degrading enzyme is explored.
ISSN:1420-682X
1420-9071
DOI:10.1007/s00018-006-6238-9