iATT liver fat quantification for steatosis grading by referring to MRI proton density fat fraction: a multicenter study

iATT liver fat quantification for steatosis grading by referring to MRI proton density fat fraction: a multicenter study

Background Several preliminary reports have suggested the utility of ultrasound attenuation coefficient measurements based on B-mode ultrasound, such as iATT, for diagnosing steatotic liver disease. Nonetheless, evidence supporting such utility is lacking. This prospective study aimed to investigate...

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Veröffentlicht in:Journal of gastroenterology 2024-06, Vol.59 (6), p.504-514
Hauptverfasser: Hirooka, Masashi, Ogawa, Sadanobu, Koizumi, Yohei, Yoshida, Yuichi, Goto, Tatsuya, Yasuda, Satoshi, Yamahira, Masahiro, Tamai, Tsutomu, Kuromatsu, Ryoko, Matsuzaki, Toshihisa, Suehiro, Tomoyuki, Kamada, Yoshihiro, Sumida, Yoshio, Hiasa, Yoichi, Toyoda, Hidenori, Kumada, Takashi
Format: Artikel
Sprache:eng
Schlagworte:
Abdominal Surgery
Adipose Tissue - diagnostic imaging
Adipose Tissue - pathology
Adult
Aged
Biliary Tract
Clinical trials
Colorectal Surgery
Fatty liver
Fatty Liver - diagnostic imaging
Fatty Liver - pathology
Female
Gastroenterology
Hepatology
Humans
Liver - diagnostic imaging
Liver - pathology
Liver diseases
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Male
Medicine
Medicine & Public Health
Middle Aged
Non-alcoholic Fatty Liver Disease - diagnostic imaging
Non-alcoholic Fatty Liver Disease - pathology
Original Article―Liver
Original ―Liver, Pancreas, and Biliary Tract
Pancreas
Prospective Studies
Reproducibility
Reproducibility of Results
ROC Curve
Severity of Illness Index
Steatosis
Surgical Oncology
Ultrasonic imaging
Ultrasonography - methods
Ultrasound
UMIN
UMIN000047411
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Zusammenfassung:Background Several preliminary reports have suggested the utility of ultrasound attenuation coefficient measurements based on B-mode ultrasound, such as iATT, for diagnosing steatotic liver disease. Nonetheless, evidence supporting such utility is lacking. This prospective study aimed to investigate whether iATT is highly concordant with magnetic resonance imaging (MRI)-based proton density fat fraction (MRI-PDFF) and could well distinguish between steatosis grades. Methods A cohort of 846 individuals underwent both iATT and MRI-PDFF assessments. Steatosis grade was defined as grade 0 with MRI-PDFF 
ISSN:0944-1174
1435-5922
DOI:10.1007/s00535-024-02096-w