Isavuconazole for the Treatment of Fungal Infections: A Real-life Experience From the Fungal Infection Network of Switzerland (FUNGINOS)

Isavuconazole for the Treatment of Fungal Infections: A Real-life Experience From the Fungal Infection Network of Switzerland (FUNGINOS)

Abstract This analysis of 116 isavuconazole therapy courses shows that hepatic test disturbances (HTDs) were relatively frequent (29% of cases) but rarely led to treatment interruption (5%). Importantly, patients with baseline HTDs, including those attributed to a first-line triazole, did not exhibi...

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Veröffentlicht in:Open Forum Infectious Diseases 2024-05, Vol.11 (5), p.ofae223-ofae223
Hauptverfasser: Couchepin, Jade, Reinhold, Ilana, Kronig, Ilona, Guidi, Monia, Buclin, Thierry, Schreiber, Peter W, Neofytos, Dionysios, Lamoth, Frederic
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Health aspects
Immunotherapy
Infectious Diseases in Special Populations
Liver
Pharmaceutical industry
Posaconazole
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Zusammenfassung:Abstract This analysis of 116 isavuconazole therapy courses shows that hepatic test disturbances (HTDs) were relatively frequent (29% of cases) but rarely led to treatment interruption (5%). Importantly, patients with baseline HTDs, including those attributed to a first-line triazole, did not exhibit a higher risk of subsequent HTD under isavuconazole therapy.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofae223