Association between a body shape index and prostate cancer: a cross-sectional study of NHANES 2001–2018
Objective Abdominal obesity, especially visceral fat, may have negative effects on the development and progression of prostate cancer (PCa). A body shape index (ABSI) can more accurately measure visceral fat accumulation. This study aimed to investigate the association between ABSI and PCa in US adu...
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| Veröffentlicht in: | International urology and nephrology 2024-06, Vol.56 (6), p.1869-1877 |
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| container_title | International urology and nephrology |
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| creator | Liu, Xiaowu Shi, Honglei Shi, Yunfeng Wei, Hanping Yuan, Xiaoliang Jiao, Zhimin Wu, Tingchun Wang, Zengjun |
| description | Objective
Abdominal obesity, especially visceral fat, may have negative effects on the development and progression of prostate cancer (PCa). A body shape index (ABSI) can more accurately measure visceral fat accumulation. This study aimed to investigate the association between ABSI and PCa in US adults.
Methods
11,013 participants were enrolled in the National Health and Nutrition Examination Survey from 2001 to 2018. Weighted multivariate logistic regression analyses were employed to explore the independent relationship between ABSI and PCa. Moreover, restricted cubic spline (RCS) analysis, subgroup analysis, and interaction tests were performed.
Results
ABSI was positively associated with the presence of PCa. When comparing the second, third, and fourth ABSI quartile to the lowest quartile, the adjusted odds ratios (95% confidence intervals) for PCa risk were 1.34 (0.77, 2.31), 1.75 (1.03, 3.00), and 1.91 (1.12, 3.27), respectively (
p
for trend = 0.011). The restricted cubic spline regression analysis did not reveal a non-linear correlation between ABSI and PCa (
p
for non-linearity = 0.076). Subgroup analysis showed a significant interaction effect in subgroups of different BMI (
p
for interaction = 0.01).
Conclusions
Elevated ABSI is significantly associated with an increased risk of PCa, particularly among individuals who are under/normal weighted or obese. |
| doi_str_mv | 10.1007/s11255-023-03917-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11090932</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2929029443</sourcerecordid><originalsourceid>FETCH-LOGICAL-c426t-69b5eb9e845715f3839e8e5382e41c54fa959c6b76b4567dca0c975d565078a53</originalsourceid><addsrcrecordid>eNp9kc1OFTEUxxuiEQRfgIVp4obN6OnXdMqG3BAUE4ILZd10OmdgyNz22s6A7HwH39AnsZeLiC5c9aTnd_7n40_IPoO3DEC_y4xxpSrgogJhmK74FtlhSouKq0Y-exJvk5c5XwOAaQBekG3RcCa1NjtkWOQc_eCmIQba4nSLGKijbezuaL5yK6RD6PAbdaGjqxTz5Cak3gWP6bBwvnzlKqNf17uR5mkuhbGn56eL85PPlAOwn99_cGDNHnneuzHjq4d3l1y8P_lyfFqdffrw8XhxVnnJ66mqTauwNdhIpZnqRSNKjKpMjJJ5JXtnlPF1q-tWqlp33oE3WnWqVqAbp8QuOdroruZ2iZ3HMCU32lUali7d2egG-3cmDFf2Mt5YxsCAEbwoHDwopPh1xjzZ5ZA9jqMLGOdsueEGuJFSFPTNP-h1nFO5RLYClBRQNq8LxTfU_bkS9o_TMLBrK-3GSlustPdW2vUUr5_u8Vjy27sCiA2QSypcYvrT-z-yvwBheKie</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3054302016</pqid></control><display><type>article</type><title>Association between a body shape index and prostate cancer: a cross-sectional study of NHANES 2001–2018</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Liu, Xiaowu ; Shi, Honglei ; Shi, Yunfeng ; Wei, Hanping ; Yuan, Xiaoliang ; Jiao, Zhimin ; Wu, Tingchun ; Wang, Zengjun</creator><creatorcontrib>Liu, Xiaowu ; Shi, Honglei ; Shi, Yunfeng ; Wei, Hanping ; Yuan, Xiaoliang ; Jiao, Zhimin ; Wu, Tingchun ; Wang, Zengjun</creatorcontrib><description>Objective
Abdominal obesity, especially visceral fat, may have negative effects on the development and progression of prostate cancer (PCa). A body shape index (ABSI) can more accurately measure visceral fat accumulation. This study aimed to investigate the association between ABSI and PCa in US adults.
Methods
11,013 participants were enrolled in the National Health and Nutrition Examination Survey from 2001 to 2018. Weighted multivariate logistic regression analyses were employed to explore the independent relationship between ABSI and PCa. Moreover, restricted cubic spline (RCS) analysis, subgroup analysis, and interaction tests were performed.
Results
ABSI was positively associated with the presence of PCa. When comparing the second, third, and fourth ABSI quartile to the lowest quartile, the adjusted odds ratios (95% confidence intervals) for PCa risk were 1.34 (0.77, 2.31), 1.75 (1.03, 3.00), and 1.91 (1.12, 3.27), respectively (
p
for trend = 0.011). The restricted cubic spline regression analysis did not reveal a non-linear correlation between ABSI and PCa (
p
for non-linearity = 0.076). Subgroup analysis showed a significant interaction effect in subgroups of different BMI (
p
for interaction = 0.01).
Conclusions
Elevated ABSI is significantly associated with an increased risk of PCa, particularly among individuals who are under/normal weighted or obese.</description><identifier>ISSN: 1573-2584</identifier><identifier>ISSN: 0301-1623</identifier><identifier>EISSN: 1573-2584</identifier><identifier>DOI: 10.1007/s11255-023-03917-2</identifier><identifier>PMID: 38214779</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Adult ; Aged ; Cross-Sectional Studies ; Humans ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Nephrology ; Nutrition Surveys ; Obesity ; Obesity, Abdominal - complications ; Obesity, Abdominal - epidemiology ; Prostate cancer ; Prostatic Neoplasms - epidemiology ; Prostatic Neoplasms - pathology ; United States - epidemiology ; Urology ; Urology - Original Paper</subject><ispartof>International urology and nephrology, 2024-06, Vol.56 (6), p.1869-1877</ispartof><rights>The Author(s) 2024</rights><rights>2024. The Author(s).</rights><rights>The Author(s) 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c426t-69b5eb9e845715f3839e8e5382e41c54fa959c6b76b4567dca0c975d565078a53</cites><orcidid>0000-0002-7583-4750</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11255-023-03917-2$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11255-023-03917-2$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38214779$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liu, Xiaowu</creatorcontrib><creatorcontrib>Shi, Honglei</creatorcontrib><creatorcontrib>Shi, Yunfeng</creatorcontrib><creatorcontrib>Wei, Hanping</creatorcontrib><creatorcontrib>Yuan, Xiaoliang</creatorcontrib><creatorcontrib>Jiao, Zhimin</creatorcontrib><creatorcontrib>Wu, Tingchun</creatorcontrib><creatorcontrib>Wang, Zengjun</creatorcontrib><title>Association between a body shape index and prostate cancer: a cross-sectional study of NHANES 2001–2018</title><title>International urology and nephrology</title><addtitle>Int Urol Nephrol</addtitle><addtitle>Int Urol Nephrol</addtitle><description>Objective
Abdominal obesity, especially visceral fat, may have negative effects on the development and progression of prostate cancer (PCa). A body shape index (ABSI) can more accurately measure visceral fat accumulation. This study aimed to investigate the association between ABSI and PCa in US adults.
Methods
11,013 participants were enrolled in the National Health and Nutrition Examination Survey from 2001 to 2018. Weighted multivariate logistic regression analyses were employed to explore the independent relationship between ABSI and PCa. Moreover, restricted cubic spline (RCS) analysis, subgroup analysis, and interaction tests were performed.
Results
ABSI was positively associated with the presence of PCa. When comparing the second, third, and fourth ABSI quartile to the lowest quartile, the adjusted odds ratios (95% confidence intervals) for PCa risk were 1.34 (0.77, 2.31), 1.75 (1.03, 3.00), and 1.91 (1.12, 3.27), respectively (
p
for trend = 0.011). The restricted cubic spline regression analysis did not reveal a non-linear correlation between ABSI and PCa (
p
for non-linearity = 0.076). Subgroup analysis showed a significant interaction effect in subgroups of different BMI (
p
for interaction = 0.01).
Conclusions
Elevated ABSI is significantly associated with an increased risk of PCa, particularly among individuals who are under/normal weighted or obese.</description><subject>Adult</subject><subject>Aged</subject><subject>Cross-Sectional Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Nephrology</subject><subject>Nutrition Surveys</subject><subject>Obesity</subject><subject>Obesity, Abdominal - complications</subject><subject>Obesity, Abdominal - epidemiology</subject><subject>Prostate cancer</subject><subject>Prostatic Neoplasms - epidemiology</subject><subject>Prostatic Neoplasms - pathology</subject><subject>United States - epidemiology</subject><subject>Urology</subject><subject>Urology - Original Paper</subject><issn>1573-2584</issn><issn>0301-1623</issn><issn>1573-2584</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><recordid>eNp9kc1OFTEUxxuiEQRfgIVp4obN6OnXdMqG3BAUE4ILZd10OmdgyNz22s6A7HwH39AnsZeLiC5c9aTnd_7n40_IPoO3DEC_y4xxpSrgogJhmK74FtlhSouKq0Y-exJvk5c5XwOAaQBekG3RcCa1NjtkWOQc_eCmIQba4nSLGKijbezuaL5yK6RD6PAbdaGjqxTz5Cak3gWP6bBwvnzlKqNf17uR5mkuhbGn56eL85PPlAOwn99_cGDNHnneuzHjq4d3l1y8P_lyfFqdffrw8XhxVnnJ66mqTauwNdhIpZnqRSNKjKpMjJJ5JXtnlPF1q-tWqlp33oE3WnWqVqAbp8QuOdroruZ2iZ3HMCU32lUali7d2egG-3cmDFf2Mt5YxsCAEbwoHDwopPh1xjzZ5ZA9jqMLGOdsueEGuJFSFPTNP-h1nFO5RLYClBRQNq8LxTfU_bkS9o_TMLBrK-3GSlustPdW2vUUr5_u8Vjy27sCiA2QSypcYvrT-z-yvwBheKie</recordid><startdate>20240601</startdate><enddate>20240601</enddate><creator>Liu, Xiaowu</creator><creator>Shi, Honglei</creator><creator>Shi, Yunfeng</creator><creator>Wei, Hanping</creator><creator>Yuan, Xiaoliang</creator><creator>Jiao, Zhimin</creator><creator>Wu, Tingchun</creator><creator>Wang, Zengjun</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>K9.</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-7583-4750</orcidid></search><sort><creationdate>20240601</creationdate><title>Association between a body shape index and prostate cancer: a cross-sectional study of NHANES 2001–2018</title><author>Liu, Xiaowu ; Shi, Honglei ; Shi, Yunfeng ; Wei, Hanping ; Yuan, Xiaoliang ; Jiao, Zhimin ; Wu, Tingchun ; Wang, Zengjun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c426t-69b5eb9e845715f3839e8e5382e41c54fa959c6b76b4567dca0c975d565078a53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Cross-Sectional Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Nephrology</topic><topic>Nutrition Surveys</topic><topic>Obesity</topic><topic>Obesity, Abdominal - complications</topic><topic>Obesity, Abdominal - epidemiology</topic><topic>Prostate cancer</topic><topic>Prostatic Neoplasms - epidemiology</topic><topic>Prostatic Neoplasms - pathology</topic><topic>United States - epidemiology</topic><topic>Urology</topic><topic>Urology - Original Paper</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liu, Xiaowu</creatorcontrib><creatorcontrib>Shi, Honglei</creatorcontrib><creatorcontrib>Shi, Yunfeng</creatorcontrib><creatorcontrib>Wei, Hanping</creatorcontrib><creatorcontrib>Yuan, Xiaoliang</creatorcontrib><creatorcontrib>Jiao, Zhimin</creatorcontrib><creatorcontrib>Wu, Tingchun</creatorcontrib><creatorcontrib>Wang, Zengjun</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International urology and nephrology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liu, Xiaowu</au><au>Shi, Honglei</au><au>Shi, Yunfeng</au><au>Wei, Hanping</au><au>Yuan, Xiaoliang</au><au>Jiao, Zhimin</au><au>Wu, Tingchun</au><au>Wang, Zengjun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association between a body shape index and prostate cancer: a cross-sectional study of NHANES 2001–2018</atitle><jtitle>International urology and nephrology</jtitle><stitle>Int Urol Nephrol</stitle><addtitle>Int Urol Nephrol</addtitle><date>2024-06-01</date><risdate>2024</risdate><volume>56</volume><issue>6</issue><spage>1869</spage><epage>1877</epage><pages>1869-1877</pages><issn>1573-2584</issn><issn>0301-1623</issn><eissn>1573-2584</eissn><abstract>Objective
Abdominal obesity, especially visceral fat, may have negative effects on the development and progression of prostate cancer (PCa). A body shape index (ABSI) can more accurately measure visceral fat accumulation. This study aimed to investigate the association between ABSI and PCa in US adults.
Methods
11,013 participants were enrolled in the National Health and Nutrition Examination Survey from 2001 to 2018. Weighted multivariate logistic regression analyses were employed to explore the independent relationship between ABSI and PCa. Moreover, restricted cubic spline (RCS) analysis, subgroup analysis, and interaction tests were performed.
Results
ABSI was positively associated with the presence of PCa. When comparing the second, third, and fourth ABSI quartile to the lowest quartile, the adjusted odds ratios (95% confidence intervals) for PCa risk were 1.34 (0.77, 2.31), 1.75 (1.03, 3.00), and 1.91 (1.12, 3.27), respectively (
p
for trend = 0.011). The restricted cubic spline regression analysis did not reveal a non-linear correlation between ABSI and PCa (
p
for non-linearity = 0.076). Subgroup analysis showed a significant interaction effect in subgroups of different BMI (
p
for interaction = 0.01).
Conclusions
Elevated ABSI is significantly associated with an increased risk of PCa, particularly among individuals who are under/normal weighted or obese.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>38214779</pmid><doi>10.1007/s11255-023-03917-2</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-7583-4750</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1573-2584 |
| ispartof | International urology and nephrology, 2024-06, Vol.56 (6), p.1869-1877 |
| issn | 1573-2584 0301-1623 1573-2584 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11090932 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Aged Cross-Sectional Studies Humans Male Medicine Medicine & Public Health Middle Aged Nephrology Nutrition Surveys Obesity Obesity, Abdominal - complications Obesity, Abdominal - epidemiology Prostate cancer Prostatic Neoplasms - epidemiology Prostatic Neoplasms - pathology United States - epidemiology Urology Urology - Original Paper |
| title | Association between a body shape index and prostate cancer: a cross-sectional study of NHANES 2001–2018 |
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