Compression Therapy in Acute Deep Venous Thrombosis of the Lower Limb and for the Prevention of Post-Thrombotic Syndrome—a Review Based on a Structured Literature Search

After an acute deep venous thrombosis (DVT) of the lower limb, 20% to 63% of patients develop post-thrombotic syndrome (PTS). In this review, we address the efficacy of compression therapy in the treatment of acute DVT of the lower limb, and for the prevention of PTS. 12 randomized controlled trials...

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Veröffentlicht in:	Deutsches Ärzteblatt international 2024-03, Vol.121 (6), p.188-194
Hauptverfasser:	Thieme, Dorothea, Linnemann, Birgit, Mühlberg, Katja, Noppeney, Thomas, Kreutz, Maria, Thieme, Marcus
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Evidence-Based Medicine Female Humans Lower Extremity - blood supply Male Postthrombotic Syndrome - etiology Postthrombotic Syndrome - prevention & control Postthrombotic Syndrome - therapy Prevalence Randomized Controlled Trials as Topic Review Risk Factors Stockings, Compression Treatment Outcome Venous Thrombosis - complications Venous Thrombosis - prevention & control Venous Thrombosis - therapy
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Zusammenfassung:	After an acute deep venous thrombosis (DVT) of the lower limb, 20% to 63% of patients develop post-thrombotic syndrome (PTS). In this review, we address the efficacy of compression therapy in the treatment of acute DVT of the lower limb, and for the prevention of PTS. 12 randomized controlled trials (RCTs) and one meta-analysis, with a total of 3751 patients, were identified in a structured literature search. Two RCTs showed that adding compression therapy to drug treatment in the first 9 days of the acute phase of lower limb DVT led to more rapid pain relief (p
ISSN:	1866-0452 1866-0452
DOI:	10.3238/arztebl.m2024.0001