Novel 1,4-substituted-1,2,3-triazoles as anti-tubercular agents
A series of 1,4-substituted-1,2,3-triazoles have been synthesized and evaluated as potential anti-tubercular agents. These compounds were assembled via click chemistry in high crude purity and in moderate to high yield. Of the compounds tested, twelve compounds showed promising anti-tubercular activ...
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| Veröffentlicht in: | ChemMedChem 2015-03, Vol.10 (5), p.787-791 |
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| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | A series of 1,4-substituted-1,2,3-triazoles have been synthesized and evaluated as potential anti-tubercular agents. These compounds were assembled via click chemistry in high crude purity and in moderate to high yield. Of the compounds tested, twelve compounds showed promising anti-tubercular activity with six possessing MIC values |
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| ISSN: | 1860-7179 1860-7187 |
| DOI: | 10.1002/cmdc.201500051 |