Pharmacokinetic-pharmacodynamic analysis of drug liking blockade by buprenorphine subcutaneous depot (CAM2038) in participants with opioid use disorder

Buprenorphine is used to treat opioid use disorder (OUD). Weekly and monthly subcutaneous long-acting buprenorphine injections (CAM2038) provide more stable buprenorphine plasma levels and reduce the treatment burden, misuse, and diversion associated with sublingual transmucosal buprenorphine formul...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2024-05, Vol.49 (6), p.1050-1057
Hauptverfasser:	Walsh, Sharon L, Comer, Sandra D, Zdovc, Jurij Aguiar, Sarr, Céline, Björnsson, Marcus, Strandgården, Kerstin, Hjelmström, Peter, Tiberg, Fredrik
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analgesics, Opioid - administration & dosage Analgesics, Opioid - pharmacokinetics Analgesics, Opioid - pharmacology Buprenorphine Buprenorphine - administration & dosage Buprenorphine - pharmacokinetics Buprenorphine - pharmacology Delayed-Action Preparations - pharmacokinetics Drug abuse Drug addiction Female Humans Hydromorphone - administration & dosage Hydromorphone - pharmacokinetics Hydromorphone - pharmacology Injections, Subcutaneous Male Middle Aged Narcotic Antagonists - administration & dosage Narcotic Antagonists - pharmacokinetics Narcotic Antagonists - pharmacology Narcotics Opiate Substitution Treatment - methods Opioid-Related Disorders - drug therapy Opioids Pharmacodynamics Pharmacokinetics Plasma Plasma levels Substance use disorder Young Adult
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