Antibody directed targeting of methotrexate-containing small unilamellar vesicles

The potential of antibody-linked SUVs containing MTX in anticancer therapy was investigated. The SUVs, mean diameter 50 +/- 20 nm, were prepared by probe sonication of MTX-containing MLVs and were covalently linked either to a RAMG or NRG. After incubation with M21 melanoma cells for 2 h, RAMG-linke...

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Veröffentlicht in:Cancer Immunology Immunotherapy 1988-08, Vol.27 (1), p.17-25
Hauptverfasser: SINGH, M, FAULKNER, G, GHOSE, T. I, MEZEI, M
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Sprache:eng
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