Antibody directed targeting of methotrexate-containing small unilamellar vesicles
The potential of antibody-linked SUVs containing MTX in anticancer therapy was investigated. The SUVs, mean diameter 50 +/- 20 nm, were prepared by probe sonication of MTX-containing MLVs and were covalently linked either to a RAMG or NRG. After incubation with M21 melanoma cells for 2 h, RAMG-linke...
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Veröffentlicht in: | Cancer Immunology Immunotherapy 1988-08, Vol.27 (1), p.17-25 |
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