Olfactory Neuroblastoma Causing Cushing's Syndrome Due to the Ectopic Adrenocorticotropic Hormone (ACTH) Secretion: A Case Report

Cushing's syndrome is a constellation of features occurring due to high blood cortisol levels. We report a case of a 47-year-old male with a history of recurrent olfactory neuroblastoma (ONB). He presented with bilateral lower limb weakness and anosmia and was found to have Cushing's syndr...

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Veröffentlicht in:	Curēus (Palo Alto, CA) CA), 2024-03, Vol.16 (3), p.e56434
Hauptverfasser:	Alsarari, Abdulrahman A, Abdulkader, Anas A, Farooqi, Waqar A, Al-Shibani, Salwa K, Al Khuwaitir, Tarig S
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Blood pressure Case reports Chemotherapy Diabetes Endocrinology/Diabetes/Metabolism Gastroesophageal reflux Hormones Hyperglycemia Hypertension Hypokalemia Internal Medicine Lymphatic system Magnetic resonance imaging Medical imaging Metastasis Neuroblastoma Neurosurgery Olfaction disorders Potassium Stains & staining Surgery Thyroid gland Tumors Urine
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Zusammenfassung:	Cushing's syndrome is a constellation of features occurring due to high blood cortisol levels. We report a case of a 47-year-old male with a history of recurrent olfactory neuroblastoma (ONB). He presented with bilateral lower limb weakness and anosmia and was found to have Cushing's syndrome due to high adrenocorticotropic hormone (ACTH) levels from an ectopic source, ONB in this case. Serum cortisol and ACTH levels declined after tumor removal.
ISSN:	2168-8184 2168-8184
DOI:	10.7759/cureus.56434