Collateral Flow: Prolonging the Ischemic Penumbra

[...]he made the statement, “In embolism the area of infarction is also greatly variable, manifestly due to variations in collateral supply. [...]Dr. Marilyn Cipolla provides an overview of how we may be able to intervene to augment the collateral circulation, preserve the penumbra (for example, before reperfusion can occur), and prevent irreversible injury [13]. [...]significant advances have been made in understanding the impact of collateral flow in stroke, but this arena of investigation is very much in evolution.