Adenosine deaminases that act on RNA, then and now

In this article, I recount my memories of key experiments that led to my entry into the RNA editing/modification field. I highlight initial observations made by the pioneers in the ADAR field, and how they fit into our current understanding of this family of enzymes. I discuss early mysteries that h...

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Veröffentlicht in:RNA (Cambridge) 2024-05, Vol.30 (5), p.521-529
1. Verfasser: Bass, Brenda L
Format: Artikel
Sprache:eng
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Zusammenfassung:In this article, I recount my memories of key experiments that led to my entry into the RNA editing/modification field. I highlight initial observations made by the pioneers in the ADAR field, and how they fit into our current understanding of this family of enzymes. I discuss early mysteries that have now been solved, as well as those that still linger. Finally, I discuss important, outstanding questions and acknowledge my hope for the future of the RNA editing/modification field.
ISSN:1355-8382
1469-9001
1469-9001
DOI:10.1261/rna.079990.124