CD44 in Bladder Cancer

CD44 in Bladder Cancer

The glycoprotein CD44, with its many isoforms and variations in carbohydrate patterning, participates in a diverse set of cellular functions. This fact leads to the protein playing a role in many normal and pathologic cellular processes including a role in cancer progression and metastasis. These sa...

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Veröffentlicht in:Cancers 2024-03, Vol.16 (6), p.1195
Hauptverfasser: Duex, Jason, Theodorescu, Dan
Format: Artikel
Sprache:eng
Schlagworte:
Amino acids
Antigens
Bladder cancer
Cancer
CD44 antigen
Cell cycle
Cell growth
Chemotherapy
Development and progression
Genomes
Health aspects
Hyaluronic acid
Immune system
Isoforms
Ligands
Lipids
Metabolism
Metastases
Metastasis
Proteins
Review
Therapeutic targets
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Beschreibung
Zusammenfassung:The glycoprotein CD44, with its many isoforms and variations in carbohydrate patterning, participates in a diverse set of cellular functions. This fact leads to the protein playing a role in many normal and pathologic cellular processes including a role in cancer progression and metastasis. These same facts make CD44 a strong therapeutic target in many cancer types, including bladder cancer.
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers16061195