Space bioprocess engineering on the horizon

Space bioprocess engineering (SBE) is an emerging multi-disciplinary field to design, realize, and manage biologically-driven technologies specifically with the goal of supporting life on long term space missions. SBE considers synthetic biology and bioprocess engineering under the extreme constraints of the conditions of space. A coherent strategy for the long term development of this field is lacking. In this Perspective, we describe the need for an expanded mandate to explore biotechnological needs of the future missions. We then identify several key parameters—metrics, deployment, and training—which together form a pathway towards the successful development and implementation of SBE technologies of the future. Space bioprocess engineering integrates synthetic biology and bioprocess engineering with the specific goal to support human life in long term space missions. In this Perspective, Berliner and colleagues describe a pathway towards the development and implementation of space bioprocessing technologies of the future.