Acetaminophen Metabolites on Presentation Following an Acute Acetaminophen Overdose (ATOM‐7)

Acetaminophen (APAP) is commonly taken in overdose and can cause acute liver injury via the toxic metabolite NAPQI formed by cytochrome (CYP) P450 pathway. We aimed to evaluate the concentrations of APAP metabolites on presentation following an acute APAP poisoning and whether these predicted the su...

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Veröffentlicht in:	Clinical pharmacology and therapeutics 2023-06, Vol.113 (6), p.1304-1314
Hauptverfasser:	Chiew, Angela L., Isbister, Geoffrey K., Stathakis, Paul, Isoardi, Katherine Z., Page, Colin, Ress, Kirsty, Chan, Betty S.H., Buckley, Nicholas A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen - therapeutic use Acetylcysteine Analgesics, Non-Narcotic - therapeutic use Australia Chemical and Drug Induced Liver Injury - diagnosis Chemical and Drug Induced Liver Injury - etiology Drug Overdose - drug therapy Humans Liver Retrospective Studies
Online-Zugang:	Volltext
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