Low infectivity among asymptomatic patients with a positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) admission test at a tertiary care center, 2020–2022

We used a strand-specific RT-qPCR to evaluate viral replication as a surrogate for infectiousness among 242 asymptomatic inpatients with a positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) admission test. Only 21 patients (9%) had detectable SARS-CoV-2 minus-strand RNA. Because most...

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Veröffentlicht in:	Infection control and hospital epidemiology 2024-02, Vol.45 (2), p.241-243
Hauptverfasser:	Tayyar, Ralph, Kiener, Melanie A., Liang, Jane W., Contreras, Gustavo, Rodriguez-Nava, Guillermo, Zimmet, Alex N., Contag, Caitlin A., Srinivasan, Krithika, McIntyre, Karen, Subramanian, Aruna, Shepard, John, Tompkins, Lucy S., Pinsky, Benjamin A., Salinas, Jorge L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Asymptomatic Clinical Laboratory Techniques Concise Communication COVID-19 COVID-19 - diagnosis COVID-19 - epidemiology COVID-19 Testing COVID-19 vaccines Diagnostic tests Disease prevention Disease transmission Epidemiology Health care Health facilities Hospitals Humans Infections Pandemics Ribonucleic acid RNA RNA, Viral - genetics SARS-CoV-2 - genetics Severe acute respiratory syndrome coronavirus 2 Tertiary Care Centers Transplants & implants Ventilation Ventilators
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Zusammenfassung:	We used a strand-specific RT-qPCR to evaluate viral replication as a surrogate for infectiousness among 242 asymptomatic inpatients with a positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) admission test. Only 21 patients (9%) had detectable SARS-CoV-2 minus-strand RNA. Because most patients were found to be noninfectious, our findings support the suspension of asymptomatic admission testing.
ISSN:	0899-823X 1559-6834
DOI:	10.1017/ice.2023.210