Clinical Benefits of Oral Anticoagulants for Elderly Patients With Cardioembolic Stroke at High Bleeding Risk

Clinical Benefits of Oral Anticoagulants for Elderly Patients With Cardioembolic Stroke at High Bleeding Risk

The relationship between the severity of cardioembolic stroke (CES) and oral anticoagulant (OAC) treatment before stroke onset in very elderly (≥80 years) patients with nonvalvular atrial fibrillation (NVAF) at high bleeding risk remains unknown. A total of 364 consecutive patients (≥80 years) with...

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Veröffentlicht in:In vivo (Athens) 2024-03, Vol.38 (2), p.725-733
Hauptverfasser: Saito, Kazumasa, Hagii, Joji, Soma, Takanobu, Washima, Shota, Yamada, Natsumi, Shiroto, Hiroshi, Saito, Shin, Kamada, Takaatsu, Takanashi, Shingo, Tomita, Hirofumi
Format: Artikel
Sprache:eng
Schlagworte:
Administration, Oral
Aged
Anticoagulants - adverse effects
Atrial Fibrillation - complications
Atrial Fibrillation - drug therapy
Embolic Stroke - chemically induced
Embolic Stroke - complications
Embolic Stroke - drug therapy
Hemorrhage - drug therapy
Hemorrhage - etiology
Humans
Retrospective Studies
Risk Factors
Stroke - diagnosis
Stroke - drug therapy
Stroke - etiology
Treatment Outcome
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Zusammenfassung:The relationship between the severity of cardioembolic stroke (CES) and oral anticoagulant (OAC) treatment before stroke onset in very elderly (≥80 years) patients with nonvalvular atrial fibrillation (NVAF) at high bleeding risk remains unknown. A total of 364 consecutive patients (≥80 years) with CES and NVAF within 48 h following stroke onset were investigated. High bleeding risk was defined as follows: Bleeding history, renal dysfunction (creatinine clearance
ISSN:0258-851X
1791-7549
DOI:10.21873/invivo.13494