The Intricate Interaction Between Expectations and Therapeutic Outcomes of Psychedelic Agents

The Intricate Interaction Between Expectations and Therapeutic Outcomes of Psychedelic Agents

Expectations affect the course of many medical conditions, impacting key measures, including long-term mortality and surgical outcomes. Expectations account for a substantial proportion of the overall therapeutic effect of some pharmacological treatments; for example, up to 50% of the effectiveness...

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Veröffentlicht in:JAMA psychiatry (Chicago, Ill.) Ill.), 2023-09, Vol.80 (9), p.867-868
Hauptverfasser: Colloca, Luana, Nikayin, Sina, Sanacora, Gerard
Format: Artikel
Sprache:eng
Schlagworte:
Hallucinogens - therapeutic use
Humans
Medical treatment
Mortality
Motivation
Pain
Surgical outcomes
Treatment Outcome
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Zusammenfassung:Expectations affect the course of many medical conditions, impacting key measures, including long-term mortality and surgical outcomes. Expectations account for a substantial proportion of the overall therapeutic effect of some pharmacological treatments; for example, up to 50% of the effectiveness of pain therapeutics may be expectation driven. Expectations can also be tempered by previous unsuccessful treatments and unfavorable encounters, diminishing therapeutic outcomes.
ISSN:2168-622X
2168-6238
DOI:10.1001/jamapsychiatry.2023.1412