Cellular rejuvenation to combat HIV-1-related neurocognitive impairment

Cellular rejuvenation to combat HIV-1-related neurocognitive impairment

HIV-1-related neurocognitive impairment affects a significant proportion of people living with HIV, and accelerated brain aging has been implicated in its pathogenesis. This forum explores the application of cellular rejuvenation strategies to target molecular mechanisms of brain aging, promote neur...

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Veröffentlicht in:Trends in microbiology (Regular ed.) 2024-01, Vol.32 (1), p.13-16
Hauptverfasser: Ostermann, Philipp N., Evering, Teresa H.
Format: Artikel
Sprache:eng
Schlagworte:
accelerated aging
Aging - pathology
Aging - psychology
Brain
cellular rejuvenation
cognitive disorders
HIV
HIV Infections - complications
HIV Infections - therapy
HIV-1
Humans
microbiology
neurocognitive decline
neurodegenerative disease
neurons
pathogenesis
Rejuvenation
senescence
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Beschreibung
Zusammenfassung:HIV-1-related neurocognitive impairment affects a significant proportion of people living with HIV, and accelerated brain aging has been implicated in its pathogenesis. This forum explores the application of cellular rejuvenation strategies to target molecular mechanisms of brain aging, promote neuronal health, and combat cognitive decline. HIV-1-related neurocognitive impairment affects a significant proportion of people living with HIV, and accelerated brain aging has been implicated in its pathogenesis. This forum explores the application of cellular rejuvenation strategies to target molecular mechanisms of brain aging, promote neuronal health, and combat cognitive decline.
ISSN:0966-842X
1878-4380
1878-4380
DOI:10.1016/j.tim.2023.09.011