Prevalence and Influencing Factors of Depression in Patients with Parkinson's Disease

The aim was to explore the prevalence and influencing factors of depression in patients with Parkinson's disease (PD). This was a cross-sectional study of the clinical data of 179 PD patients for retrospective analysis. Using the self-rating depression scale (SDS) and the Hamilton depression scale-21 (HAMD-21), we evaluated the prevalence of depression and analyzed the factors influencing depression in PD. The prevalence of depression in PD patients was 45.25%, and the degree of depression was mainly mild to moderate. Sleep status, daily use of levodopa, a high Hoehn and Yahr stage, a high unified Parkinson's disease rating scale (UPDRS) II score, and a high UPDRS III score were all risk factors for depression in PD patients. The prevalence of depression in PD patients is high, and the degree of depression is closely related to many factors, which should receive close attention in clinical work.