Extracellular release of antigenic proteins by Helicobacter pylori
Screening a Helicobacter pylori genomic library with antisera raised against H. pylori broth culture supernatant resulted in the identification of six antigens: urease, HspB, Lpp20, DnaK, MsrA, and a cysteine-rich 28-kDa protein (designated HcpA). H. pylori antigens may be released into the extracel...
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| Veröffentlicht in: | Infection and immunity 1998-06, Vol.66 (6), p.2984-2986 |
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| container_issue | 6 |
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| container_title | Infection and immunity |
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| creator | PING CAO MCCLAIN, M. S FORSYTH, M. H COVER, T. L |
| description | Screening a Helicobacter pylori genomic library with antisera raised against H. pylori broth culture supernatant resulted in the identification of six antigens: urease, HspB, Lpp20, DnaK, MsrA, and a cysteine-rich 28-kDa protein (designated HcpA). H. pylori antigens may be released into the extracellular space by multiple mechanisms, including specific secretion pathways, autolysis, and membrane vesicle formation. |
| doi_str_mv | 10.1128/iai.66.6.2984-2986.1998 |
| format | Article |
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Psychology</subject><subject>Genomic Library</subject><subject>Heat-Shock Proteins - genetics</subject><subject>Heat-Shock Proteins - metabolism</subject><subject>Helicobacter pylori - genetics</subject><subject>Helicobacter pylori - immunology</subject><subject>Helicobacter pylori - metabolism</subject><subject>Hemolysin Proteins</subject><subject>HSP70 Heat-Shock Proteins - genetics</subject><subject>HSP70 Heat-Shock Proteins - metabolism</subject><subject>Lipoproteins - genetics</subject><subject>Lipoproteins - metabolism</subject><subject>Membrane Transport Proteins</subject><subject>Microbiology</subject><subject>Molecular and Cellular Pathogenesis</subject><subject>Molecular Sequence Data</subject><subject>Permeability, membrane transport, intracellular transport</subject><subject>Plasmids - genetics</subject><subject>Sequence Analysis, DNA</subject><subject>Sequence Homology, Amino Acid</subject><issn>0019-9567</issn><issn>1098-5522</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVUE1v1DAQtVBRWQo_AZFDxS3B4_jzwKGtlnalSlzgbNnupBh548XOVt1_T6KuVvQyo9F7b-bNI-Qz0A6A6a_RxU7KTnbMaN7ORXZgjH5DVkCNboVg7IysKAXTGiHVO_K-1j_zyDnX5-TcCCOVUityvX6eiguY0j650hRM6Co2eWjcOMVHHGNodiVPGMfa-ENzhymG7F2YsDS7Q8olfiBvB5cqfjz2C_Lr-_rnzV17_-N2c3N13wauYGo1eEDlA3oTmPaKAjPCQVA915orYxAFIPIhMO-VAi2ZF_TBmUH0AyL2F-Tby97d3m_xIeA4O092V-LWlYPNLtrXyBh_28f8ZIFqZsys_3LUl_x3j3Wy21iXz92IeV8tSK6plnQmqhdiKLnWgsPpBlC7pG83VxsrpZV2SX8p0i7pz8pP_1s86Y5xz_jlEXc1uDQUN4ZYTzTWM9Ci7_8BpHuQVw</recordid><startdate>19980601</startdate><enddate>19980601</enddate><creator>PING CAO</creator><creator>MCCLAIN, M. 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L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Extracellular release of antigenic proteins by Helicobacter pylori</atitle><jtitle>Infection and immunity</jtitle><addtitle>Infect Immun</addtitle><date>1998-06-01</date><risdate>1998</risdate><volume>66</volume><issue>6</issue><spage>2984</spage><epage>2986</epage><pages>2984-2986</pages><issn>0019-9567</issn><eissn>1098-5522</eissn><coden>INFIBR</coden><abstract>Screening a Helicobacter pylori genomic library with antisera raised against H. pylori broth culture supernatant resulted in the identification of six antigens: urease, HspB, Lpp20, DnaK, MsrA, and a cysteine-rich 28-kDa protein (designated HcpA). 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| ispartof | Infection and immunity, 1998-06, Vol.66 (6), p.2984-2986 |
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| language | eng |
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| source | American Society for Microbiology; MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Amino Acid Sequence Antigens, Bacterial - genetics Antigens, Bacterial - metabolism Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacteriology Biological and medical sciences Escherichia coli Proteins Fundamental and applied biological sciences. Psychology Genomic Library Heat-Shock Proteins - genetics Heat-Shock Proteins - metabolism Helicobacter pylori - genetics Helicobacter pylori - immunology Helicobacter pylori - metabolism Hemolysin Proteins HSP70 Heat-Shock Proteins - genetics HSP70 Heat-Shock Proteins - metabolism Lipoproteins - genetics Lipoproteins - metabolism Membrane Transport Proteins Microbiology Molecular and Cellular Pathogenesis Molecular Sequence Data Permeability, membrane transport, intracellular transport Plasmids - genetics Sequence Analysis, DNA Sequence Homology, Amino Acid |
| title | Extracellular release of antigenic proteins by Helicobacter pylori |
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