Lactate dehydrogenase‐to‐albumin ratio: A superior inflammatory marker for predicting contrast‐associated acute kidney injury after percutaneous coronary intervention

Purpose Inflammation is commonly considered a mechanism underlying contrast‐associated acute kidney injury (CA‐AKI). This study aimed to explore the predictive capability of the novel inflammatory marker lactate dehydrogenase‐to‐albumin ratio (LAR) for CA‐AKI following percutaneous coronary intervention (PCI), and further compare it with other common inflammatory biomarkers. Methods This study enrolled 5,435 patients undergoing elective PCI. The primary outcome was CA‐AKI, and the secondary outcome was all‐cause mortality. All patients were grouped into three groups based on the LAR tertiles. Results Three hundred fifteen patients (5.8%) experienced CA‐AKI during hospitalization. The fully adjusted logistic regression suggested a significant increase in the risk of CA‐AKI in LAR Tertile 3 (odds ratio [OR]: 2.51, 95% confidence interval [CI]: 1.68−3.83, p