Doxycycline Prophylaxis to Prevent Sexually Transmitted Infections in Women

Doxycycline postexposure prophylaxis has been shown to prevent STIs in cisgender men and transgender women. In this trial involving cisgender women in Kenya, STI incidence was not lower with doxycycline than with standard care.

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Veröffentlicht in:	The New England journal of medicine 2023-12, Vol.389 (25), p.2331-2340
Hauptverfasser:	Stewart, Jenell, Oware, Kevin, Donnell, Deborah, Violette, Lauren R., Odoyo, Josephine, Soge, Olusegun O., Scoville, Caitlin W., Omollo, Victor, Mogaka, Felix O., Sesay, Fredericka A., McClelland, R. Scott, Spinelli, Matthew, Gandhi, Monica, Bukusi, Elizabeth A., Baeten, Jared M.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS Antibiotics Bacterial Infections Birth control Chlamydia Chlamydia Infections - drug therapy Chlamydia trachomatis Disease prevention Doxycycline Doxycycline - adverse effects Female Genetic testing Global Health Gonorrhea Hair Hair analysis HIV HIV Infections - drug therapy HIV Infections - epidemiology HIV Infections - prevention & control Homosexuality, Male Human immunodeficiency virus Humans Hypothesis testing Infections Infectious Disease Infectious Disease General Kenya - epidemiology Male Neisseria gonorrhoeae Plasma Pre-Exposure Prophylaxis Pregnancy Prophylaxis Sexually transmitted diseases Sexually Transmitted Diseases - drug therapy Sexually Transmitted Diseases - epidemiology Sexually Transmitted Diseases - prevention & control STD Syphilis Unsafe Sex Womens health
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Beschreibung
Zusammenfassung:	Doxycycline postexposure prophylaxis has been shown to prevent STIs in cisgender men and transgender women. In this trial involving cisgender women in Kenya, STI incidence was not lower with doxycycline than with standard care.
ISSN:	0028-4793 1533-4406 1533-4406
DOI:	10.1056/NEJMoa2304007