Serosurveillance among urban slum and non-slum populations immunized with COVID-19 vaccines in Bangladesh

Using two rounds of serosurveillance, we aimed to observe the COVID-19 vaccination status and the dynamics of antibody responses to different vaccines among urban slum and non-slum populations of Bangladesh. Adults (>18 years) and children (10–17 years) were enrolled in March and October 2022. Da...

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Veröffentlicht in:Epidemiology and infection 2024-01, Vol.152, p.e14
Hauptverfasser: Sarker, Protim, Haq, Md Ahsanul, Akhtar, Evana, Roy, Anjan Kumar, Hosen, Md Biplob, Huda, Tarique Mohammad Nurul, Akter, Sharmin, Ahmed, Razu, Chowdhury, Md Razib, Ferdous, Jannatul, Vandenent, Maya, Islam, Mohammad Zahirul, Zaman, Rashid U., Arifeen, Shams-El, Razzaque, Abdur, Raqib, Rubhana
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Sprache:eng
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Zusammenfassung:Using two rounds of serosurveillance, we aimed to observe the COVID-19 vaccination status and the dynamics of antibody responses to different vaccines among urban slum and non-slum populations of Bangladesh. Adults (>18 years) and children (10–17 years) were enrolled in March and October 2022. Data including COVID-19 vaccine types and dosage uptake were collected. SARS-CoV-2 spike (S)-specific antibodies were measured in blood. The proportion of vaccinated children was significantly lower among slum than non-slum populations. Two doses of vaccines showed an increase in the level of anti-S-antibodies up to 2 months, followed by reduced levels at 2–6 months and a resurgence at 6–12 months. Children showed significantly higher anti-S-antibodies after two doses of the Pfizer–BioNTech vaccine than adults; however, after 6 months, the level of antibodies declined in younger children (10 -
ISSN:0950-2688
1469-4409
1469-4409
DOI:10.1017/S0950268823001942