Influence of p16 Protein Immunostaining on Histopathological Features of Pleomorphic Adenoma and Carcinoma ex- Pleomorphic Adenoma

Influence of p16 Protein Immunostaining on Histopathological Features of Pleomorphic Adenoma and Carcinoma ex- Pleomorphic Adenoma

The objective of this study was to evaluate the role of p16 in histologic characteristics and transition of Pleomorphic Adenoma (PA) to Carcinoma ex-PA (CxPA). So, 60 PA and 4 CxPA were histologic reviewed based on microscopic characteristics proposed by Hellquist, Triantafyllou and Dulguerov (PA) a...

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Veröffentlicht in:Asian Pacific Journal of Cancer Prevention 2023-11, Vol.24 (11), p.3815-3824
Hauptverfasser: Magalhaes, Iana Aragao, Barbosa, Kecynara Costa, Costa, Gabriella Alves Juliao, Oliveira Filho, Osias Vieira De, Da Silva Junior, Jose Erialdo, Gonzaga Silva, Lucio Flavio, Juaçaba, Sergio Ferreira, Sousa, Fabricio Bitu, Barros Silva, Paulo Goberlanio De
Format: Artikel
Sprache:eng
Schlagworte:
Adenocarcinoma
Adenoma, Pleomorphic
Cyclin-Dependent Kinase Inhibitor p16
Epithelial Cells
Humans
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Zusammenfassung:The objective of this study was to evaluate the role of p16 in histologic characteristics and transition of Pleomorphic Adenoma (PA) to Carcinoma ex-PA (CxPA). So, 60 PA and 4 CxPA were histologic reviewed based on microscopic characteristics proposed by Hellquist, Triantafyllou and Dulguerov (PA) and Morais, Antony and Toluie (CxPA). Immunostaining for p16 was associated in different parenchyma and stroma of both tumors and Fisher's/chi-square tests and Mann-Whitney test were performed (SPSS v20.0, p
ISSN:2476-762X
1513-7368
2476-762X
DOI:10.31557/APJCP.2023.24.11.3815