Changes in Primary HIV-1 Drug Resistance Due to War Migration from Eastern Europe

In recent years, especially as a result of war in Ukraine, enormous movements of migration to Poland from eastern European countries have been reported, including people living with Human Immunodeficiency Virus (HIV). We have conducted multi-center, prospective study, which aimed to establish HIV-1...

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Veröffentlicht in:Journal of immigrant and minority health 2024-02, Vol.26 (1), p.15-22
Hauptverfasser: Załęski, Andrzej, Lembas, Agnieszka, Dyda, Tomasz, Siwak, Ewa, Osińska, Joanna, Suchacz, Magdalena, Stempkowska-Rejek, Justyna, Strycharz, Marta, Orzechowska, Justyna, Wiercińska-Drapało, Alicja
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Sprache:eng
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Zusammenfassung:In recent years, especially as a result of war in Ukraine, enormous movements of migration to Poland from eastern European countries have been reported, including people living with Human Immunodeficiency Virus (HIV). We have conducted multi-center, prospective study, which aimed to establish HIV-1 subtype and assess the presence of primary drug resistance mutations to nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors and protease inhibitors in antiretroviral treatment naïve patients. The clinical trial recruited 117 individuals during 2 years period (2020–2022). The prevalence of HIV-1 subtype A was statistically significantly more frequent in Ukrainian, and HIV-1 subtype B in Polish patients (p  0.05), nevertheless Polish patients had multidrug resistance mutations more frequent (p 
ISSN:1557-1912
1557-1920
DOI:10.1007/s10903-023-01559-1