Adjunctive posterior wall isolation for the treatment of persistent and longstanding persistent atrial fibrillation (CORNERSTONE AF) trial: Design and rationale

Background A left atrial posterior wall isolation (LAPWI) is one of the atrial fibrillation (AF) ablation strategies. Hypothesis We hypothesized that an additional empirical LAPWI would increase the freedom from recurrent atrial arrhythmias as compared to standard AF ablation in persistent AF patien...

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Veröffentlicht in:	Clinical cardiology (Mahwah, N.J.) N.J.), 2024-01, Vol.47 (1), p.e24164-n/a
Hauptverfasser:	Shigeta, Takatoshi, Miyazaki, Shinsuke, Inaba, Osamu, Inamura, Yukihiro, Nitta, Junichi, Sekiguchi, Yukio, Takahashi, Atsushi, Hachiya, Hitoshi, Nagata, Yasutoshi, Yamauchi, Yasuteru, Hayashi, Tatsuya, Iwai, Shinsuke, Mizukami, Akira, Ono, Yuichi, Handa, Keita, Suzuki, Makoto, Suzuki, Atsushi, Nakajima, Jun, Hirao, Kenzo, Okada, Hiroyuki, Negishi, Miho, Ikenouchi, Takashi, Yamamoto, Tasuku, Goto, Kentaro, Nishimura, Takuro, Tao, Susumu, Takigawa, Masateru, Hirakawa, Akihiro, Goya, Masahiko, Sasano, Tetsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Aged atrial fibrillation Atrial Fibrillation - surgery Cardiac arrhythmia catheter ablation Catheter Ablation - methods Catheters Clinical Study Design complication Esophagus Female Heart Atria Humans Investigations Male Meta-analysis Middle Aged Multicenter Studies as Topic posterior Prospective Studies pulmonary vein isolation Pulmonary Veins - surgery Randomized Controlled Trials as Topic Recurrence Review boards Treatment Outcome wall isolation
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Zusammenfassung:	Background A left atrial posterior wall isolation (LAPWI) is one of the atrial fibrillation (AF) ablation strategies. Hypothesis We hypothesized that an additional empirical LAPWI would increase the freedom from recurrent atrial arrhythmias as compared to standard AF ablation in persistent AF patients. Methods The CORNERSTONE AF study is a prospective, randomized, multicenter study investigating patients with AF persisting for >7 days and
ISSN:	0160-9289 1932-8737
DOI:	10.1002/clc.24164