Systematic identification and characterization of genes in the regulation and biogenesis of photosynthetic machinery

Photosynthesis is central to food production and the Earth’s biogeochemistry, yet the molecular basis for its regulation remains poorly understood. Here, using high-throughput genetics in the model eukaryotic alga Chlamydomonas reinhardtii, we identify with high confidence (false discovery rate [FDR...

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Veröffentlicht in:	Cell 2023-12, Vol.186 (25), p.5638-5655.e25
Hauptverfasser:	Kafri, Moshe, Patena, Weronika, Martin, Lance, Wang, Lianyong, Gomer, Gillian, Ergun, Sabrina L., Sirkejyan, Arthur K., Goh, Audrey, Wilson, Alexandra T., Gavrilenko, Sophia E., Breker, Michal, Roichman, Asael, McWhite, Claire D., Rabinowitz, Joshua D., Cross, Frederick R., Wühr, Martin, Jonikas, Martin C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chlamydomonas reinhardtii - genetics Chlamydomonas reinhardtii - metabolism Chloroplasts - genetics Chloroplasts - metabolism Gene Expression Regulation genetics methionyl-tRNA formyltransferase Mutation photosynthesis Photosynthesis - genetics photosystem I maturation factors protein localization protein profiling Proteins - genetics Proteins - metabolism retrograde regulation Ribosomes - genetics Ribosomes - metabolism RNA sequencing RNA, Messenger - genetics
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Beschreibung
Zusammenfassung:	Photosynthesis is central to food production and the Earth’s biogeochemistry, yet the molecular basis for its regulation remains poorly understood. Here, using high-throughput genetics in the model eukaryotic alga Chlamydomonas reinhardtii, we identify with high confidence (false discovery rate [FDR]
ISSN:	0092-8674 1097-4172
DOI:	10.1016/j.cell.2023.11.007