Anticoagulant therapy and home blood pressure-associated risk for stroke/bleeding events in elderly patients with non-valvular atrial fibrillation: the sub-cohort study of ANAFIE registry

Anticoagulant therapy and home blood pressure-associated risk for stroke/bleeding events in elderly patients with non-valvular atrial fibrillation: the sub-cohort study of ANAFIE registry

The benefits of direct oral anticoagulants (DOACs) and warfarin in elderly Japanese patients with non-valvular atrial fibrillation (NVAF) and high home systolic blood pressure (H-SBP) are unclear. This sub-cohort study of the ANAFIE Registry estimated the incidence of clinical outcomes in patients r...

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Veröffentlicht in:Hypertension research 2023-12, Vol.46 (12), p.2575-2582
Hauptverfasser: Kario, Kazuomi, Hasebe, Naoyuki, Okumura, Ken, Yamashita, Takeshi, Akao, Masaharu, Atarashi, Hirotsugu, Ikeda, Takanori, Koretsune, Yukihiro, Shimizu, Wataru, Suzuki, Shinya, Tsutsui, Hiroyuki, Toyoda, Kazunori, Hirayama, Atsushi, Yasaka, Masahiro, Yamaguchi, Takenori, Teramukai, Satoshi, Kimura, Tetsuya, Morishima, Yoshiyuki, Takita, Atsushi, Inoue, Hiroshi
Format: Artikel
Sprache:eng
Schlagworte:
Administration, Oral
Aged
Anticoagulants
Anticoagulants - adverse effects
Atrial Fibrillation - complications
Atrial Fibrillation - drug therapy
Atrial Fibrillation - epidemiology
Blood Pressure
Cardiac arrhythmia
Cohort analysis
Cohort Studies
Hemorrhage - chemically induced
Hemorrhage - drug therapy
Hemorrhage - epidemiology
Humans
Hypertension
Older people
Registries
Risk Factors
Stroke
Stroke - epidemiology
Stroke - etiology
Stroke - prevention & control
Warfarin - adverse effects
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Zusammenfassung:The benefits of direct oral anticoagulants (DOACs) and warfarin in elderly Japanese patients with non-valvular atrial fibrillation (NVAF) and high home systolic blood pressure (H-SBP) are unclear. This sub-cohort study of the ANAFIE Registry estimated the incidence of clinical outcomes in patients receiving anticoagulant therapy (warfarin and DOACs) stratified by H-SBP levels (
ISSN:0916-9636
1348-4214
DOI:10.1038/s41440-023-01361-4