Economic and Social Standing of Individuals in Iran Diagnosed with Multiple Sclerosis

Multiple sclerosis (MS) may be affected by socioeconomic status (SES). This study aims to explore the determinants of SES among Iranian patients with MS and examine how these factors relate to disability and disease progression. All patients with MS listed in the nationwide MS registry of Iran (NMSRI) until January 8, 2022, were included in this population-based study. Among the 5153 patients, most were female (74.5%), married (70.8%), and did not hold an academic degree (53.8%). Unemployment (OR: 3.75) and being unmarried (OR: 2.60) were significantly associated with Expanded Disability Status Scale (EDSS)≥6, and the time to progression was shorter in the unemployed group ( value: 0.03). There was also a significant negative correlation between the time to progression and the age at disease onset. The study suggests that providing financial and social support to MS patients and their families through investment could reduce both individual and societal burdens.