68Ga-PSMA-11 PET/CT in Bilateral Clear Cell Renal Cell Carcinoma: an Intra-patient Comparison Between High and Low Grade Tumors

Recent studies have outlined the emerging role of 68 Ga-PSMA-11 PET/CT in the diagnostic algorithm of clear cell renal cell carcinoma (ccRCC). We report a unique intra-patient comparison of bilateral primary ccRCC imaged with 68 Ga-PSMA-11 PET/CT. Although both tumors resulted 68 Ga-PSMA-11 avid, we...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nuclear medicine and molecular imaging 2023-12, Vol.57 (6), p.298-300
Hauptverfasser:	Urso, Luca, Rocca, Giovanni Christian, Conti, Grazia Maria, Colella, Alessandro, Nieri, Alberto, Cittanti, Corrado, Ippolito, Carmelo, Bartolomei, Mirco
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Cardiology Computed tomography Imaging Interesting Image Medicine Medicine & Public Health Nuclear Medicine Oncology Orthopedics Radiology Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Recent studies have outlined the emerging role of 68 Ga-PSMA-11 PET/CT in the diagnostic algorithm of clear cell renal cell carcinoma (ccRCC). We report a unique intra-patient comparison of bilateral primary ccRCC imaged with 68 Ga-PSMA-11 PET/CT. Although both tumors resulted 68 Ga-PSMA-11 avid, we found a remarkable discrepancy in uptake intensity between the high grade and the low grade ccRCC. This case confirms previous evidence reporting that SUVmax on 68 Ga-PSMA-11 PET/CT could be used to discriminate aggressive high grade from more indolent low grade ccRCC, due to their different endothelial expression of PSMA.
ISSN:	1869-3474 1869-3482
DOI:	10.1007/s13139-023-00805-6