Efficacy of low-dose lung radiotherapy in the management of COVID-19 patients: a randomised, open-label study

Efficacy of low-dose lung radiotherapy in the management of COVID-19 patients: a randomised, open-label study

Evaluate role of low-dose radiotherapy (LDRT) in COVID-19 pneumonia. Sixty-five patients 40 years or older tested positive for COVID-19 reverse transcriptase-polymerase chain reaction with mild to moderate acute respiratory distress syndrome (ARDS), were randomised 1:1, from 4 June 2021, to either b...

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Veröffentlicht in:British journal of radiology 2023-12, Vol.96 (1152), p.20230022
Hauptverfasser: Dinakar, Kootala, Jakka, Mohan Krishna, Vemannagari, Pavan Kumar Reddy, Mohan, Alladi, Subramanian, Bala Venkat, Bodagala, Vijayalakshmi Devi, Bhuma, Vengamma, Das, Pranabandhu, Bonala, Sreenivasa Rao, Vutukuru, Venkatarami Reddy
Format: Artikel
Sprache:eng
Schlagworte:
COVID-19
Humans
India
Lung
Respiratory Distress Syndrome
SARS-CoV-2
Treatment Outcome
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Zusammenfassung:Evaluate role of low-dose radiotherapy (LDRT) in COVID-19 pneumonia. Sixty-five patients 40 years or older tested positive for COVID-19 reverse transcriptase-polymerase chain reaction with mild to moderate acute respiratory distress syndrome (ARDS), were randomised 1:1, from 4 June 2021, to either best standard of care (control arm) according to the Indian Council of Medical Research guidelines or a single dose of LDRT (LDRT-0.5Gy) to both lungs along with best standard of care (experimental arm). The primary outcome was either progression to severe disease (PaO2/FiO2 ratio
ISSN:0007-1285
1748-880X
1748-880X
DOI:10.1259/bjr.20230022