Renal denervation for uncontrolled hypertension
Renal denervation (RDN) is a minimally invasive catheter-based intervention that uses 1 of a range of techniques to disrupt renal afferent and efferent nerve signals between the kidney and brain. Renal denervation reduces office systolic blood pressure by an average of 4-6 mm Hg more than control pa...
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Veröffentlicht in: | Canadian Medical Association journal (CMAJ) 2023-11, Vol.195 (43), p.E1475-E1480 |
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creator | Marcusohn, Erez Tobe, Sheldon W Dueck, Andrew Madan, Mina |
description | Renal denervation (RDN) is a minimally invasive catheter-based intervention that uses 1 of a range of techniques to disrupt renal afferent and efferent nerve signals between the kidney and brain. Renal denervation reduces office systolic blood pressure by an average of 4-6 mm Hg more than control patients and is proposed as an adjunctive treatment to pharmacotherapy for patients with uncontrolled hypertension. Serious complications from renal denervation are uncommon, and minor access site complications occur in around 5% of patients. Renal denervation is best provided by a multidisciplinary team including hypertension specialists and interventionalists. |
doi_str_mv | 10.1503/cmaj.230745 |
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Renal denervation reduces office systolic blood pressure by an average of 4-6 mm Hg more than control patients and is proposed as an adjunctive treatment to pharmacotherapy for patients with uncontrolled hypertension. Serious complications from renal denervation are uncommon, and minor access site complications occur in around 5% of patients. 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subjects | Ablation Alcohol Antihypertensive drugs Antihypertensives Blood Care and treatment Catheters Clinical trials Denervation Diagnosis Drug therapy Endorsements Evaluation Hypertension Intubation Kidneys Medical colleges Nervous system Patients Pharmacology Practice Regulatory approval Ultrasonic imaging Veins & arteries |
title | Renal denervation for uncontrolled hypertension |
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