Renal denervation for uncontrolled hypertension

Renal denervation (RDN) is a minimally invasive catheter-based intervention that uses 1 of a range of techniques to disrupt renal afferent and efferent nerve signals between the kidney and brain. Renal denervation reduces office systolic blood pressure by an average of 4-6 mm Hg more than control patients and is proposed as an adjunctive treatment to pharmacotherapy for patients with uncontrolled hypertension. Serious complications from renal denervation are uncommon, and minor access site complications occur in around 5% of patients. Renal denervation is best provided by a multidisciplinary team including hypertension specialists and interventionalists.