Fetal marrow suppression after maternal chemotherapy for leukaemia

A preterm baby, whose mother received chemotherapy for acute leukaemia during pregnancy, required intensive care because of profound anaemia and neutropenia. Haemopoietic progenitor cell studies showed fetal marrow suppression. Those caring for such mothers and babies should know the possible seriou...

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Bibliographische Detailangaben
Veröffentlicht in:	Archives of disease in childhood. Fetal and neonatal edition 1994-11, Vol.71 (3), p.F209-F210
Hauptverfasser:	Murray, N A, Acolet, D, Deane, M, Price, J, Roberts, I A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult Anemia - chemically induced Anemia - therapy Antineoplastic Combined Chemotherapy Protocols - adverse effects Chemotherapy Erythropoietin - therapeutic use Etoposide - adverse effects Female Granulocyte Colony-Stimulating Factor - therapeutic use Humans Infant, Newborn Infant, Premature, Diseases - chemically induced Infant, Premature, Diseases - therapy Leukemia Leukemia, Myeloid - drug therapy Neutropenia - chemically induced Neutropenia - therapy Pregnancy Pregnancy Complications, Neoplastic - drug therapy Prenatal Exposure Delayed Effects
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Beschreibung
Zusammenfassung:	A preterm baby, whose mother received chemotherapy for acute leukaemia during pregnancy, required intensive care because of profound anaemia and neutropenia. Haemopoietic progenitor cell studies showed fetal marrow suppression. Those caring for such mothers and babies should know the possible serious effects chemotherapy for malignancies can have on a developing fetus. Long term follow up of the baby is imperative.
ISSN:	1359-2998 1468-2052
DOI:	10.1136/fn.71.3.F209