The Prognostic Significance of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio for Long-Term Survival in Patients With Severe Left Ventricular Dysfunction and Implantable Cardioverter Defibrillator

İntroduction: Systemic inflammation resulting from comorbidities such as arterial hypertension, diabetes, and obesity is responsible for the pathogenesis of myocardial structural and functional changes in heart failure. The neutrophil-to-lymphocyte ratio (NLR) and platelet‐to‐lymphocyte ratio (PLR)...

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Veröffentlicht in:	Curēus (Palo Alto, CA) CA), 2023-10, Vol.15 (10), p.e47441-e47441
1. Verfasser:	Çakır, Mustafa Ozan
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Blood Blood platelets Body mass index Cardiac arrhythmia Cardiac/Thoracic/Vascular Surgery Cardiology Cardiovascular disease Chronic obstructive pulmonary disease Coronary vessels Demographics Diabetes Heart attacks Heart failure Hypertension Laboratories Lymphocytes Medical prognosis Mortality Outpatient care facilities Patients Peptides Proteins Regression analysis Variables Vein & artery diseases
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Zusammenfassung:	İntroduction: Systemic inflammation resulting from comorbidities such as arterial hypertension, diabetes, and obesity is responsible for the pathogenesis of myocardial structural and functional changes in heart failure. The neutrophil-to-lymphocyte ratio (NLR) and platelet‐to‐lymphocyte ratio (PLR) are novel biomarkers of inflammation. The aim of this study was to evaluate the relationship between blood NLR and PLR levels and one-year cardiac mortality in primary prevention patients with left ventricular ejection fraction (LVEF) ≤35%, using an intracardiac defibrillator.Methods: A total of 180 compensated heart failure patients with LVEF
ISSN:	2168-8184 2168-8184
DOI:	10.7759/cureus.47441