PRALIMAP-CINECO Cohort: 10-year post-intervention weight trajectories of PRALIMAP-INES adolescents

Abstract Background Between 2012 and 2015, the PRALIMAP-INES trial was carried-out in the France including 1143 adolescents aged 13-18 years old and aimed at reducing weight social inequalities in adolescence. The main result showed that a proportionate universalism principle is an effective way to reduce weight social inequalities in adolescence. About 10 years later, the PRALIMAP-Cineco study aims to investigate the social, economic, educational and health trajectories among PRALIMAP-INES participants. Methods Young adults are contacted by clinical research team and invited to participate to the follow-up. If they agree, they are asked to complete a self-reported questionnaire (sociodemographic, diet, tobacco, alcohol, physical activity, sedentary behaviour, quality of life) and then invited to realise a medical visit for global check-up including weight measures. Results Inclusion is currently in progress and 248 participants are contacted (Male: 130, 52.4%). The mean BMI is 28.5±5.4 kg/m2, 40% of overweight and 30.7% obesity. Among overweight/obese adolescents, 80.1% remain overweight/obese (50.5% of overweight adolescents remain overweight while 67.6% of obese remain obese in adulthood) and 19.9% switch to normal weight in adulthood. No significant difference is observed between advantaged with standard intervention (81.3%) and less advantaged with strengthened intervention (80.7%) groups. Conclusions Post-intervention follow-up suggest that overweight/obesity in adolescence is strongly predictive of overweight/obesity in adulthood without differential trajectories according to socioeconomic status. It would be very interesting to investigate the profile of overweight adolescents who switch to normal to understand the determinants of this favourable trajectory. Key messages • Adolescents with overweight or obesity are more likely to be overweight or obese in adulthood confirming the need of early age public health prevention programmes. • Lifelong prevention is also necessary to ensure more effective public policy.