Genomic Analysis of Group B Streptococcus Carriage Isolates From Botswana Reveals Distinct Local Epidemiology and Identifies Novel Strains

Genomic Analysis of Group B Streptococcus Carriage Isolates From Botswana Reveals Distinct Local Epidemiology and Identifies Novel Strains

Abstract In pregnant people colonized with group B Streptococcus (GBS) in Botswana, we report the presence/expansion of sequence types 223 and 109, a low rate of erythromycin resistance, and 3 novel sequence types. These data highlight the importance of local epidemiologic studies of GBS, a signific...

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Veröffentlicht in:Open Forum Infectious Diseases 2023-10, Vol.10 (10), p.ofad496-ofad496
Hauptverfasser: Hanze Villavicencio, Karen L, Job, Megan J, Burghard, Anne Claire, Taffet, Allison, Banda, Francis M, Vurayai, Moses, Mokomane, Margaret, Arscott-Mills, Tonya, Mazhani, Tiny, Nchingane, Seeletso, Thomas, Brady, Steenhoff, Andrew P, Ratner, Adam J
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Brief Report
Disease transmission
Diseases
Epidemiology
Erythromycin
Infants (Newborn)
Meningitis
Neonatology
Pregnant women
Risk factors
Tetracycline
Tetracyclines
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Zusammenfassung:Abstract In pregnant people colonized with group B Streptococcus (GBS) in Botswana, we report the presence/expansion of sequence types 223 and 109, a low rate of erythromycin resistance, and 3 novel sequence types. These data highlight the importance of local epidemiologic studies of GBS, a significant source of neonatal disease.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofad496