A high-throughput structural system biology approach to increase structure representation of proteins from Clostridioides difficile

A high-throughput structural system biology approach to increase structure representation of proteins from Clostridioides difficile

causes life-threatening gastrointestinal infections. It is a high-risk pathogen due to a lack of effective treatments, antimicrobial resistance, and a poorly conserved genomic core. Herein, we report 30 X-ray structures from a structure genomics pipeline spanning 13 years, representing 10.2% of the...

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Veröffentlicht in:Microbiology resource announcements 2023-10, Vol.12 (10), p.e0050723
Hauptverfasser: Rosas-Lemus, Monica, Dey, Supratim, Minasov, George, Tan, Kemin, Anderson, Spencer M, Brunzelle, Joseph, Nocadello, Salvatore, Shabalin, Ivan, Filippova, Ekaterina, Halavaty, Andrei, Kim, Youngchang, Maltseva, Natalia, Osipiuk, Jerzy, Minor, Wladek, Joachimiak, Andrzej, Savchenko, Alexei, Anderson, Wayne F, Satchell, Karla J F
Format: Artikel
Sprache:eng
Schlagworte:
Bacteriology
Other Genetic Resources
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Zusammenfassung:causes life-threatening gastrointestinal infections. It is a high-risk pathogen due to a lack of effective treatments, antimicrobial resistance, and a poorly conserved genomic core. Herein, we report 30 X-ray structures from a structure genomics pipeline spanning 13 years, representing 10.2% of the X-ray structures for this important pathogen.
ISSN:2576-098X
2576-098X
DOI:10.1128/MRA.00507-23