OR29-05 Sarcopenia, Low Bone Mineral Density And Hidden Obesity In Young Adult Men Living With HIV (MLWH): Prevalence And Relationship With Sex Steroids

Disclosure: S. De Vincentis: None. M. Decaroli: None. C. Greco: None. C. Diazzi: None. F. Fanelli: None. M. Mezzullo: None. U. Pagotto: None. G. Guaraldi: None. V. Rochira: None. Background: HIV is associated with decreased bone mineral density (BMD) and decreased muscle mass. Osteoporosis and sarcopenia often co-exist and their onset is multifactorial. Sex steroids play a key role in the homeostasis of bone health and body composition in HIV-uninfected men, but data about their role in MLWH are scanty. AIM: To investigate the frequency of low BMD and sarcopenia and their relationship with gonadal function in MLWH younger than 50. Methodology: Prospective, cross-sectional, observational study on MLWH with ongoing antiretroviral therapy. Body composition and BMD were obtained by dual-energy X-ray absorptiometry (DXA). Sarcopenia was defined as appendicular lean mass/height2 (ALMI)