Structure and function of the apical PIKKs in double-strand break repair

Members of the phosphatidylinositol 3ʹ kinase (PI3K)-related kinases (PIKKs) family, including DNA-dependent protein kinase catalytic subunit (DNA-PKcs), ataxia telangiectasia mutated (ATM), ataxia-telangiectasia mutated and Rad3-related (ATR), mammalian target of rapamycin (mTOR), suppressor with m...

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Veröffentlicht in:	Current opinion in structural biology 2023-10, Vol.82, p.102651-102651, Article 102651
Hauptverfasser:	Xu, Jingfei, Bradley, Noah, He, Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Ataxia Telangiectasia Mutated Proteins - genetics Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism DNA - metabolism DNA Damage DNA Repair Phosphorylation Protein Serine-Threonine Kinases - genetics Protein Serine-Threonine Kinases - metabolism Signal Transduction Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - metabolism
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