Young-onset Rectal Cancer: Unique Tumoral Microbiome and Correlation with Response to Neoadjuvant Therapy
External exposures, the host, and the microbiome interact in oncology. We aimed to investigate tumoral microbiomes in young-onset rectal cancers (YORCs) for profiles potentially correlative with disease etiology and biology. YORC is rapidly increasing, with 1 in 4 new rectal cancer cases occurring u...
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Veröffentlicht in: | Annals of surgery 2023-10, Vol.278 (4), p.538-548 |
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Hauptverfasser: | , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | External exposures, the host, and the microbiome interact in oncology. We aimed to investigate tumoral microbiomes in young-onset rectal cancers (YORCs) for profiles potentially correlative with disease etiology and biology.
YORC is rapidly increasing, with 1 in 4 new rectal cancer cases occurring under the age of 50 years. Its etiology is unknown.
YORC ( |
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ISSN: | 0003-4932 1528-1140 1528-1140 |
DOI: | 10.1097/SLA.0000000000006015 |