A giant mass in the eyelid: Peripheral T-Cell lymphoma, not otherwise specified

Purpose: To report a case with an unusual giant mass in the eyelid which was diagnosed as peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS). Methods: A 40-year-old woman was referred with a 1-year history of rapidly and constantly growing eyelid mass. Results: The patient underwent an incisional biopsy and histopathological examination revealed a PTCL-NOS. After achieving regression by the combination of cyclophosphamide, hydroxydoxorubicin, vincristine (oncovin), etoposide, and prednisolone therapy, the remaining crusts were debrided, the eyelids were separated, and the wound was left to heal by secondary intention. Cicatricial ectropion of the lower eyelid occurred during follow-up and it was corrected with a free skin graft successfully. Conclusion: PTCL-NOS is uncommon but it may reach massive dimensions in the eyelid region.