Analysis of risk factors for the progression and prognosis of connective tissue disease-associated interstitial lung disease

Objectives: This study aimed to investigate the risk factors of lung progression in patients with connective tissue disease-associated interstitial lung disease (ILD). Patients and methods: A total of 91 ILD patients (28 males, 63 females; mean age: 54.9 [+ or -] 11.3 years; range, 30 to 77 years) were included in the prospective follow-up study conducted throughout 2020. They were divided into progressors (n=27) and nonprogressors (n=64) according to whether the pulmonary disease progressed during a six- month follow-up period. The clinical data of the two groups were analyzed, and a logistic regression model was constructed to analyze the risk factors of the progression of ILD in all patients. Results: Univariate analysis revealed significant differences (p