Oestrogen receptor low positive breast cancer: associations with prognosis

Oestrogen receptor low positive breast cancer: associations with prognosis

Purpose In this study of oestrogen receptor (ER) Low Positive breast cancers (BC) in three large cohorts of BC patients, we assess associations between levels of ER expression and tumour characteristics and prognosis. Methods Cases were stratified into patients unlikely to have received adjuvant the...

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Veröffentlicht in:Breast cancer research and treatment 2023-10, Vol.201 (3), p.535-545
Hauptverfasser: Skjervold, Anette H., Valla, Marit, Bofin, Anna M.
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers, Tumor - metabolism
Breast cancer
Breast Neoplasms - pathology
Cancer
Cancer research
Diagnosis
ErbB-2 protein
Estrogen
Estrogen receptors
Female
Humans
Medicine
Medicine & Public Health
Oncology
Oncology, Experimental
Original Laboratory Investigation
Prognosis
Proportional Hazards Models
Receptor, ErbB-2 - metabolism
Receptors, Estrogen - metabolism
Receptors, Progesterone - metabolism
Tumors
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Zusammenfassung:Purpose In this study of oestrogen receptor (ER) Low Positive breast cancers (BC) in three large cohorts of BC patients, we assess associations between levels of ER expression and tumour characteristics and prognosis. Methods Cases were stratified into patients unlikely to have received adjuvant therapy according to treatment guidelines at time of diagnosis (before 1995), and those who could have received adjuvant therapy (diagnosed in 1995 or later). ER status was divided into 
ISSN:0167-6806
1573-7217
DOI:10.1007/s10549-023-07040-9