Lung dopaminergic nerves facilitate the establishment of T helper 2 resident memory cells in early life

Lung dopaminergic nerves facilitate the establishment of T helper 2 resident memory cells in early life

Our study identifies the dopamine-DRD4 signaling pathway as a therapeutic target to modify the progression of allergic asthma from childhood to adulthood.

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Veröffentlicht in:Journal of allergy and clinical immunology 2023-02, Vol.152 (2), p.386-399
Hauptverfasser: Wang, Wei, Garcia, Carolyn, Shao, Fengzhi, Cohen, Jonathan A., Bai, Yan, Fine, Alan, Ai, Xingbin
Format: Artikel
Sprache:eng
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Zusammenfassung:Our study identifies the dopamine-DRD4 signaling pathway as a therapeutic target to modify the progression of allergic asthma from childhood to adulthood.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2023.02.011