Noninvasive Fibrosis Assessment in Chronic Hepatitis C Infection: An Update

Liver biopsy is historically the gold standard for liver fibrosis assessment of chronic hepatitis C patients. However, with the introduction and validation of noninvasive tests (NITs) to evaluate advanced fibrosis, and the direct-acting antiviral agents for treatment of chronic hepatitis C virus (HC...

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Veröffentlicht in:Journal of clinical and translational hepatology 2023-10, Vol.11 (5), p.1228-1238
Hauptverfasser: Bojanic, Kristina, Bogojevic, Mirta Sudaric, Vukadin, Sonja, Sikora, Renata, Ivanac, Gordana, Lucic, Nikola Raguz, Smolic, Martina, Tabll, Ashraf A, Wu, George Y, Smolic, Robert
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Sprache:eng
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Zusammenfassung:Liver biopsy is historically the gold standard for liver fibrosis assessment of chronic hepatitis C patients. However, with the introduction and validation of noninvasive tests (NITs) to evaluate advanced fibrosis, and the direct-acting antiviral agents for treatment of chronic hepatitis C virus (HCV), the role of NITs have become even more complex. There is now need for longitudinal monitoring and elucidation of cutoff values for prediction of liver-related complication after sustained virological response. The aim of this report is to provide a critical overview of the various NITs available for the assessment of liver fibrosis in HCV patients.
ISSN:2225-0719
2310-8819
DOI:10.14218/JCTH.2022.00365