The NLRP3 inflammasome in viral infection (Review)
The interplay between pathogen and host determines the immune response during viral infection. The Nod‑like receptor (NLR) protein 3 inflammasome is a multiprotein complex that induces the activation of inflammatory caspases and the release of IL‑1β, which play an important role in the innate immune...
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| Veröffentlicht in: | Molecular medicine reports 2023-09, Vol.28 (3), Article 160 |
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| container_title | Molecular medicine reports |
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| creator | Zheng, Qiaoli Hua, Chunting Liang, Qichang Cheng, Hao |
| description | The interplay between pathogen and host determines the immune response during viral infection. The Nod‑like receptor (NLR) protein 3 inflammasome is a multiprotein complex that induces the activation of inflammatory caspases and the release of IL‑1β, which play an important role in the innate immune responses. In the present review, the mechanisms of the NLR family pyrin domain containing 3 inflammasome activation and its dysregulation in viral infection were addressed. |
| doi_str_mv | 10.3892/mmr.2023.13047 |
| format | Article |
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The Nod‑like receptor (NLR) protein 3 inflammasome is a multiprotein complex that induces the activation of inflammatory caspases and the release of IL‑1β, which play an important role in the innate immune responses. 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The Nod‑like receptor (NLR) protein 3 inflammasome is a multiprotein complex that induces the activation of inflammatory caspases and the release of IL‑1β, which play an important role in the innate immune responses. 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| fulltext | fulltext |
| identifier | ISSN: 1791-2997 |
| ispartof | Molecular medicine reports, 2023-09, Vol.28 (3), Article 160 |
| issn | 1791-2997 1791-3004 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10407610 |
| source | Spandidos Publications Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Apoptosis Cytokines Health aspects Immune response Inflammasomes Inflammation Innate immunity Kinases Mitochondrial DNA Proteins Pyrin protein Review Viral infections |
| title | The NLRP3 inflammasome in viral infection (Review) |
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