A case report: A rare case of icteric variant of Stauffer's syndrome

Stauffer's syndrome is a rare paraneoplastic non metastatic hepatic dysfunction related to renal cell carcinoma. It is characterized by elevated alkaline phosphatase, erythrocyte sedimentation rate, a-2-globulin, y-glutamyl transferase, thrombocytosis, prolongation of prothrombin time and hepatosplenomegaly, in the absence of hepatic metastasis. A rare variant of it with cholestatic jaundice is described in four cases so far in literature. We present a case of a patient presented with features of cholestatic jaundice who was found to have a left sided renal cell carcinoma in the work up. This case illustrates the importance of considering paraneoplastic syndromes in mind when working up for patients presenting with hepatic dysfunctions without identifiable causes. This may result in early identification and intervention which will result in better outcome and prolong survival rate.