The Sperm DNA Fragmentation Assay with SDF Level Less Than 15% Provides a Useful Prediction for Clinical Pregnancy and Live Birth for Women Aged under 40 Years

The Sperm DNA Fragmentation Assay with SDF Level Less Than 15% Provides a Useful Prediction for Clinical Pregnancy and Live Birth for Women Aged under 40 Years

This retrospective cohort study was conducted on 1148 males who presented along with their partners for infertility management at the PIVET Medical Centre between 2013 and 2022 and had a sperm DNA fragmentation (SDF) assay performed by Halosperm, thereafter participating in 1600 assisted reproductiv...

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Veröffentlicht in:Journal of personalized medicine 2023-06, Vol.13 (7), p.1079
Hauptverfasser: Chua, Shiao Chuan, Yovich, Steven John, Hinchliffe, Peter Michael, Yovich, John Lui
Format: Artikel
Sprache:eng
Schlagworte:
Birth
Clinical outcomes
DNA
DNA damage
DNA fragmentation
Fertilization
Gestational age
In vitro fertilization
Infertility
Laboratories
Males
Metaphase
Miscarriage
Oocytes
Precision medicine
Pregnancy
Pregnant women
Reproductive technologies
Sperm
Spermatozoa
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Beschreibung
Zusammenfassung:This retrospective cohort study was conducted on 1148 males who presented along with their partners for infertility management at the PIVET Medical Centre between 2013 and 2022 and had a sperm DNA fragmentation (SDF) assay performed by Halosperm, thereafter participating in 1600 assisted reproductive technology (ART) cycles utilising one of three modalities, namely, IVF-Only, ICSI-Only or IVF-ICSI Split cycles. The outcomes from the ART cycles were then analysed as two groups based on SDF levels
ISSN:2075-4426
2075-4426
DOI:10.3390/jpm13071079