Exeporfinium chloride (XF-73) nasal gel dosed over 24 hours prior to surgery significantly reduced Staphylococcus aureus nasal carriage in cardiac surgery patients: Safety and efficacy results from a randomized placebo-controlled phase 2 study

Exeporfinium chloride (XF-73) nasal gel dosed over 24 hours prior to surgery significantly reduced Staphylococcus aureus nasal carriage in cardiac surgery patients: Safety and efficacy results from a randomized placebo-controlled phase 2 study

We studied 83 cardiac-surgery patients with nasal S. aureus carriage who received 4 intranasal administrations of XF-73 nasal gel or placebo

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Bibliographische Detailangaben
Veröffentlicht in:Infection control and hospital epidemiology 2023-07, Vol.44 (7), p.1171-1173
Hauptverfasser: Mangino, Julie E., Firstenberg, Michael S., Milewski, Rita K.C., Rhys-Williams, William, Lees, James P., Dane, Aaron, Love, William G., Gonzalez Moreno, Jesus
Format: Artikel
Sprache:eng
Schlagworte:
Antibiotics
Bone surgery
Clinical trials
Concise Communication
Heart surgery
Infectious diseases
Laboratories
Patients
Skin
Staphylococcus infections
Transplants & implants
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Zusammenfassung:We studied 83 cardiac-surgery patients with nasal S. aureus carriage who received 4 intranasal administrations of XF-73 nasal gel or placebo
ISSN:0899-823X
1559-6834
DOI:10.1017/ice.2023.17